Glossary

Volunteer subjects used to study normal physiology and behavior or who do not have the condition under study in a particular protocol, used as comparisons with subjects who do have the condition. "Normal" may not mean normal in all respects. For example, patients with broken legs (if not on medication that will affect the results) may serve as normal volunteers in studies of metabolism, cognitive development, and the like. Similarly, patients with heart disease but without diabetes may be the "normals" in a study of diabetes complicated by heart disease.

Natural Occurring Radioactive Materials

A cellulose or nylon membrane to which RNA molecules have been attached by capillary action. The transferred RNA is hybridized to single-stranded DNA probes. Northern blot technique is often used to measure expression (transcription) of a gene for which a specific cDNA is available for use as a probe.

Similar to Southern blotting, except that RNA is transferred onto a matrix and the presence of a specific RNA molecule is detected by DNA-RNA hybridization.

Drug substance is protected from exposure to the environment during processing.

Mono-nitrogen oxides (NO - nitric oxide, NO2 - nitrogen dioxide)

National Pharmaceutical Association

Niemann-Pick Disease, Type C

National Pollutant Discharge Elimination System (EPA)

The National Pollution Discharge Elimination System permit required by, and issued by EPA.

National Primary Drinking Water Regulations (FDA)

Potable Water (Water meeting EPA National Primary Drinking Water Regulations).

National Priorities List

Nonpurgeable Organic Carbon

Novel Protein Production Systems

Notice of Proposed Rule-Making

Nominal Pipe Size

National Pipe Thread

Net Present Value

Natural Rubber

National Research Council

Nuclear Regulatory Commission

National Renewable Energy Laboratory (United States)

Nonsteroidal Anti-Inflammatory Drug