Glossary

The concentration of soluble minerals (mainly salts of the alkali metals or of magnesium) in water.

The presence of soluble minerals in water.

A large genus of the tribe Salmonellae, family Enterobacteriaceae, containing motile, gram-negative, rod-shaped organisms that ferment dextrose, forming acid and usually gas. Several species occur as intestinal pathogens in acute inflammations in humans and domestic animals. Salmonella typhimurium causes food poisoning in humans.

Neutral compound formed of two or more ions. The salt disassociates into cations and anions when dissolved in water.

A compound formed by the interaction of an acid and a base, the hydrogen atoms of the acid being replaced by another positive ion derived from the base.

In reverse osmosis, the ratio of salts removed (rejected) to the original salt concentration.

Plasma obtained by centrifugation of outdated (older than 21 days) whole blood. This type of plasma is difficult to convert to serum because most coagulation factors have lost their activity.

The name give to plasma originally collected as Source Plasma, but because of its exposure to storage temperatures in excess of 10o C, or its collection during a period of noncompliance (usually, material in inventory at the time of license suspension due to deviations which occurred during the manufacturing of those units, and which affect or may affect the safety, purity, or potency of the plasma) is not permitted to be used as a licensed product. It is restricted to use in the manufacture of products not subject to license under Section 351 of the Public Health Service Act.

Scientific Apparatus Makers Association

Substance Abuse and Mental Health Services Administration

Includes the Center for Substance Abuse Prevention, the Center for Substance Abuse Treatment and the Center on Mental Health Services. Previously the Alcohol, Drug Abuse, and Mental Health Administration (ADAMHA).

To take a small but representative portion of a much larger stream where the sample collected, accurately represents the content of the larger stream.

While the biopharmaceutical industry has used this description in the past, and many in the industry continue to use it, every sample point should have a specific purpose; therefore, it is recommended that this designation be abandoned for being vague and non-specific.

Styrene-Acrylonitrile

Storage Area Network

A widely used method of determining the order of bases in DNA.

A misnomer for "Hygienic Design". The term Sanitary Design is no longer in use by the industry in the context of this definition.A system of design that meets standards, specification, codes, regulatory and industrial guidelines, and acceptable engineering design methods to reach a degree of sanitation required by food, pharmaceutical, and cosmetics processing.

That part of decontamination that reduces viable microorganisms to a defined acceptance level; normally achieved by using a chemical agent or heat to reduce microbial levels.

That part of decontamination that reduces viable microorganisms to a defined acceptance level; normally achieved by using a chemical agent or heat to reduce microbial levels.

To make sanitary by cleaning or disinfecting. That part of decontamination that reduces viable microorganisms to a defined acceptance level normally achieved by using a chemical agent, steam or dry heat.

(USP <1072>) An agent for reducing, on inanimate surfaces, the number of all forms of microbial life including fungi, viruses, and bacteria.

Alkaline hydrolysis of triacyl glycerols to yield fatty acids as soaps.

A type of cancer that starts in bone or muscle.

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